Your doctor has prescribed Savella® (milnacipran HCl) to help you get some relief from your fibromyalgia. This website was created to give you important information about taking Savella.

Savella is approved for the management of fibromyalgia. It has been shown to help people feel less pain and improve their fibromyalgia overall, and improve their physical function, all at the same time.

Even if you were recently diagnosed with fibromyalgia, you’ve probably spent months, or even years, dealing with your symptoms. Like other fibromyalgia patients, you are trying to manage your condition so that you can get back to more of the daily activites you need to do.

What to Expect
from Savella

What results will you
see, and when?

Taking Savella

Following your healthcare provider’s instructions.

Lifestyle Changes

These simple lifestyle changes may help.

Tools & Resources

Fibromyalgia Tracker, Doctor Discussion Guide, and more.

Register Now

Information and support for the treatment of fibromyalgia.

 

Savella (milnacipran HCl) is indicated for the management of fibromyalgia in adults. Savella is available by prescription only.

Important Risk Information About Savella

  • Savella is not used to treat depression, but it acts like medicines that are used to treat depression (antidepressants) and other psychiatric disorders.
  • Antidepressants can increase suicidal thoughts in children, teens, and young adults. Savella is not approved for use in patients under the age of 18.
  • Patients on antidepressants and their families or caregivers should watch for new or worsening symptoms, unusual changes in behavior, thoughts of suicide, anxiety, agitation, panic attacks, difficulty sleeping, irritability, hostility, aggressiveness, impulsivity, restlessness, or extreme hyperactivity.
  • Call your healthcare provider right away if you have thoughts of suicide or if any of these symptoms are severe or occur suddenly. Be especially observant within the first few months of treatment or whenever the dose is increased or decreased.
  • For more information about this risk, please read the Savella Patient Medication Guide in the Full Prescribing Information.

Who should NOT take Savella?

Do not take Savella if you:

  • Are taking, or have recently taken, a type of drug called a monoamine oxidase inhibitor (MAOI)
  • Have uncontrolled narrow-angle glaucoma (increased eye pressure)

What should I tell my healthcare provider before taking Savella?

Before starting Savella, tell your healthcare provider about all your medical conditions, including if you have:

  • Hypertension (high blood pressure), heart rhythm problems, fast heart rate, or other heart diseases
  • Liver problems or a history of substantial alcohol use
  • Kidney problems or difficulty passing urine, including painful urination
  • Current or past manic episodes or seizure disorders
  • Bleeding disorders
  • Glaucoma

Also, to avoid a potentially serious or life-threatening condition, tell your healthcare provider if you are taking, or are planning to take, any prescription or over-the-counter medications, including:

  • Medication prescribed for a psychiatric or neurological condition including other selective serotonin and norepinephrine reuptake inhibitors (SNRIs), selective serotonin reuptake inhibitors (SSRIs), certain migraine or headache medications (triptans), or tryptophan
  • NSAID pain relievers (such as ibuprofen or naproxen), aspirin, warfarin, or other blood thinners
  • Diuretics

Tell your healthcare provider if you are pregnant, planning to become pregnant during therapy, or breastfeeding.

What other important information should I discuss with my healthcare provider?

Your blood pressure and pulse should be monitored at regular intervals when receiving treatment with Savella.

You should not operate machinery or drive until you are reasonably certain that Savella treatment does not affect your ability to engage in such activities. Avoid drinking alcohol while taking Savella.

Call your doctor if you have very high fever, rigid muscles, shaking, confusion, or rapid changes in heart rate and blood pressure. These may be signs of a rare, but serious, side effect.

Talk with your healthcare provider before stopping Savella or changing your dose. Withdrawal symptoms can occur, particularly when discontinuation is abrupt.

What are the most common side effects of Savella?

The most common side effect associated with Savella treatment is nausea. Other common side effects are headache, constipation, dizziness, insomnia, hot flush, hyperhidrosis (excessive sweating), vomiting, palpitations, increased heart rate, dry mouth, and hypertension. This is not a complete list of side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA.
Visit www.fda.gov/Safety/MedWatch.

Please see Full Prescribing Information.